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  • Made with world’s best Ashwagandha
  • Relieve Stress
  • Relieve Anxiety
  • Creates Calmness

Tranquil is an all-natural anxiety aid. Our formula contains ingredients that research has shown to help calm and relieve stress and anxiety.

100% natural

Tranquil is an all-natural anxiety aid.  Our formula contains ingredients that research has shown to help calm and relieve stress and anxiety.

So how can Tranquil help?

Tranquil is an all-natural anxiety aid.  Our formula contains ingredients that research has shown to help calm and relieve stress and anxiety.

The purpose of creating a new anxiety/stress nutraceutical product is to bring to the market a supplement that is highly efficacious in treating, naturally, symptoms of stress and anxiety. Currently, many products are on the market claiming to help reduce these symptoms but often, the supplements are of little to no effect to the customer. This pervasive problem is due to low dosages of specific ingredients and the minimal content of ingredients in these supplements. With my new anxiety/stress product, I aim to bridge this gap and bring to the market a non-drug formulation that is significantly more effective than any other natural supplement on the market and, for the same price, or less, than competing products. This concept mirrors my REMSleep©product and is the basis for my creating Pfeiffer Formulas; to create superior micro-nutritional supplementation for optimal mental health functioning.

This formulation should be taken in the morning/afternoons and then, if needed, REMSleep©can be added in the evenings for better sleep. I formulated this product to be taken as both a stand-alone supplement and to be taken in conjunction with REMSleep©, if the customer has additional need at bedtime.


5-HTP – 5-HTP has been shown in scientific studies to promote relaxation and alleviate stress and anxiety. The relaxation and anti-anxiety properties of 5-HTP appear to come from its ability to elevate levels of serotonin. Research has demonstrated that 5-HTP may reduce the risks of panic attacks and symptoms of panic, as well as anxiety and emotional stress. Research also indicates 5-HTP may be effective in helping to alleviate depression. In the rapidly growing field of integrative psychiatry, prescription medications and natural supplements are often used in combination to improve treatment response and reduce side effects resulting when medications are taken alone. 5-HTP is an example of a natural supplement that may be safely combined with a prescription anti-anxiety medication with little risk of adverse effects. In one study, patients randomized to 5-HTP in combination with carbidopa (a drug that inhibits the enzyme that breaks down 5-HTP in the peripheral blood supply, thus increasing the amount of 5-HTP that enters the brain) reported reductions in anxiety comparable to patients treated with an anti-anxiety medication. In contrast, patients who received a placebo did not improve.

GABA – As a natural chemical the body produces, GABA’s primary role is to diminish the activity of neurons in the brain and central nervous system, which puts the body in a greater state of relaxation and alleviates stress and anxiety. Supplemental GABA can benefit sleep by aiding relaxation and providing relief from anxiety and stress. Some studies have shown GABA to be effective in lowering anxiety and boosting relaxation. For example, one small study of 13 adults showed GABA to be effective as a relaxant and anxiety reliever, with slowed brain waves seen within an hour of taking the supplement. This study also found that a boost to the immune system also occurred with GABA, suggesting supplemental GABA may enhance immunity in people undergoing mental stress. Another larger study investigated the effects of 100 milligrams of GABA among a group of people who’d recently undertaken a stressful mental task. Scientists measured a slowing down of brain waves in people who’d taken GABA, pointing to an alleviation of mental stress. Another study tested the effects of GABA in people who were about to take a stressful math test. Those who ate chocolate infused with GABA rebounded more quickly from test-related stress, including stress-lowering changes to heart-rate variability.

L – Theanine – L-theanine promotes relaxation and facilitates sleep by contributing to a number of changes in the brain:

  • Boosts levels of GABA and other calming brain chemicals. L-theanine elevates levels of GABA, as well as serotonin and dopamine. These chemicals are known as neurotransmitters, and they work in the brain to regulate emotions, mood, concentration, alertness, and sleep, as well as appetite, energy, and other cognitive skills. Increasing levels of these calming brain chemicals promotes relaxation and can help with sleep.
  • Lowers levels of “excitatory” brain chemicals. At the same time, it is increasing chemicals that promote feelings of calm, L-theanine also reduces levels of chemicals in the brain that are linked to stress and anxiety. This may also be a way that L-theanine can protect brain cells against stress and age-related damage.
  • Enhances alpha brain waves. Alpha brain waves are associated with a state of “wakeful relaxation.” That’s the state of mind you experience when meditating, being creative, or letting your mind wander in daydreaming. Alpha waves are also present during REM sleep. L-theanine appears to trigger the release of alpha-waves, which enhances relaxation, focus, and creativity.
  • One of the appealing aspects of L-theanine is that it works to relax without sedating. That can make L-theanine a good choice for people who are looking to enhance their “wakeful relaxation,” without worrying about becoming sleepy and fatigued during the day.

Benefits of L-theanine – Reducing stress and anxiety. L-theanine is what’s known as an anxiolytic—it works to reduce anxiety. Some anxiolytics, such as valerian and hops, have sedative effects. L-theanine, on the other hand, promotes relaxation and stress reduction without sedating. L-theanine can help
foster a state of calm, attentive wakefulness. L-theanine has positive effects on both the mental and physical symptoms of stress, including lowering heart rate and blood pressure. Research suggests that L-theanine can help reduce anxiety in people with schizophrenia and schizoaffective disorder.

Enhancing attention, focus, memory and learning. Under stress, the body increases production of certain hormones, including cortisol and corticosterone. These hormone changes inhibit some brain activity, including memory formation and spatial learning. L-theanine helps to lower levels of the stress hormone corticosterone and avoid the interference with memory and learning.

L-theanine may help boost other cognitive skills. Research shows L-theanine can increase attention span and reaction time in people who are prone to anxiety. It may help improve accuracy—one study shows that taking L-theanine reduced the number of errors made in a test of attention. Sometimes, L-theanine is used with caffeine to enhance cognitive skills. Studies show that combinations of L-theanine and caffeine can improve attention span, enhance the ability to process visual information, and increase accuracy when switching from one task to another.

Taurine – Taurine is an amino acid that plays an important role in the brain as a neurotransmitter and neuromodulator inhibitor. It also has a similar composition to GABA and L-Glycine which both act as stabilizer and can be used to calm an excited brain. Its action basically regulates the sodium and potassium levels inside the cells as well as the levels of magnesium outside and in between cells which helps in controlling the electrical cellular activity and cell to cell communications. Anti-anxiety and anti-convulsant properties can be traced to the amino acid taurine as stated by several cases done by medical professionals. Taurine supplements are useful for treating minor problems like migraine, insomnia, restlessness and irritability. It is also being in use for certain cases of alcoholism, depression, obsession, mania and hypomania.

KSM-66 Ashwagandha – Clinically, ashwagandha is found to be very helpful to calm anxiety, and specifically, help agoraphobia (anxiety especially in open or crowded places). In a 2012 study, of 64 randomized volunteers, asked subjects to take either ashwagandha or a placebo twice a day for 60 days. The
ashwagandha group’s capsule contained 300 mg of a concentrated extract made from the root. During the treatment period, regular telephone call check-ins assured volunteers were consistently taking the herbs or placebo and were used to note any adverse reactions. The treatment group given the ashwagandha root extract exhibited a significant reduction in anxiety scores after two months relative to the placebo group, without side effects. Most notably, serum cortisol levels were substantially reduced in the herbal group (Chandrasekhar et al., 2012). Cortisol is the stress hormone that goes up when we are stressed out. Cortisol also creates longer-term fatigue and mental fogginess, and brain structures for emotion and memory are damaged when cortisol is too high.

Other case studies using ashwagandha also show benefit in stressed women with adrenal hyperplasia (enlarged adrenal glands) showing beneficial changes in cortisol, progesterone, and pregnenolone (a valuable precursor hormone), as well as a noticeable improvement in a difficult to treat hair loss known as alopecia (Kalani, 2012). Other studies of men with stress-related fertility issues found higher antioxidant status and much healthier sperm when
supplemented with ashwagandha.

Magnesium Chloride – Magnesium works to increase and stimulate GABA production in the brain. Magnesium reduces stress hormones present in the body. Magnesium is anti-inflammatory. Magnesium helps to remove heavy metals from the body. Magnesium plays a leading role in brain plasticity – the
creation of new brain cells, new neural connections, increases effectiveness of cognitive behavioral therapy when used to treat anxiety, and helps the brain to rewire itself to be naturally less anxious. Magnesium lifts depression thereby reducing symptoms of associated stress and anxiety as it’s responsible for over 300 chemical actions/reactions in the body, more than any single mineral. Magnesium helps to keep blood sugar levels stable. Magnesium is
known to improve overall mental wellbeing.

Zinc Picolinate – One of the most extensive studies took place in Australia. The so-called “Australian Longitudinal Study on Women’s Health” encouraged 58,000 women to submit all manner of health-related information. The results of this study, after completion, were then analyzed to identify trends,
patterns and relationships. The data collected included both a dietary questionnaire and a survey designed to assess levels of depression in the participants. The results demonstrated a very clear pattern, in that the less zinc consumed in the diet the greater the likelihood of suffering from depressive symptoms like anxiety. Furthermore, the differences between the top and bottom segments of the population were significant; individuals consuming the most zinc were 30-50% less likely to suffer from depression than those consuming the least.

This trend has been further verified in other studies. For example, one investigation recruited both individuals that had been diagnosed with clinical depression and those that were deemed to be perfectly healthy. Blood samples were drawn, and the results from both groups were compared. It was found that lower zinc levels appeared to be associated with symptoms of depression, however the impact was far greater among women. This trend line was even stronger when comparing women using antidepressant medications at the time of the study. The experts in question concluded that “inadequate dietary zinc intake contributes to depressive symptoms in women” and furthermore that “zinc is a beneficial adjunct to antidepressant therapy in women”. Another similar study found that, on average, zinc levels in the blood tend to be 22% lower among individuals suffering from anxiety.

The scientific research up to this point seems clear – depressive symptoms like anxiety tend to be closely correlated with low levels of zinc in the body. However, correlation does not necessarily prove causation. The next question is whether raising levels of zinc through diet or supplementation reduces feelings of anxiousness. In one study the zinc levels of individuals suffering from anorexia were monitored. Their levels were found to be considerably below the recommended level. The question was whether these levels had fallen to their recorded levels due to a lack of dietary intake, or whether these low levels of zinc themselves were having an impact on cases of anorexia nervosa. To test this concept, the participants were provided with either 50mg of zinc per day or an identical-looking placebo, to see what impact the rising zinc concentration had on their condition. It was found that the group receiving zinc supplementation experienced considerable improvements in feelings of depression and anxiety when compared with the placebo group.

Another study supplemented patients previously defined as having “major depression” with 25mg of zinc sulphate per day to take alongside their already-prescribed antidepressants. Despite their existing medication routine, it was found that after 12 weeks their depression showed signs of improvement. The results of this study, again, demonstrate the benefits of zinc for anxiety and also demonstrate that people already taking medication may benefit further
from zinc supplementation.

Lastly, zinc has been shown to benefit cases of chronic mild stress, in which consuming just 10mg of zinc per kilogram of bodyweight exhibited a “rapid antidepressant-like effect” in as little as a week. It is little wonder, then, that one group of scientists studying the effect of zinc on anxiety concluded that “not only has zinc deficiency been shown to induce depression-like and anxiety-like behaviors, supplementation has been used as a treatment for major

Selenium – Selenium has shown to improve mood by reducing inflammation, which is often at heightened levels when someone has a mood disorder, such as anxiety. Selenium is also an antioxidant, which helps prevent cell damage. It is also anti-carcinogenic, which helps to prevent cancer from developing. Selenium deficiency has been linked to autoimmune conditions,  Hashimoto’s, diabetes, cancer, and mortality. Other studies have linked selenium deficiency to depression and negative mood, including stress/anxiety.

Vitamin D3 (cholecalciferol) – Roughly 60% to 80% of the US population are vitamin D deficient, whether mildly, moderately, or severely. Vitamin D deficiency can cause and/or exacerbate depression/anxiety, bone softening (low bone density) or fractures, fatigue and generalized weakness, muscle cramps and weakness, joint pain (most noticeable in the back and knees), blood sugar dysregulation, low immunity, low calcium levels in the blood, mood changes and irritability, and weight gain (increasing D levels can lead to healthy weight loss).

Vitamin C – Vitamin C helps reduce both the physical and psychological effects of stress on people. People who have high levels of vitamin C do not show the expected mental and physical signs of stress when subjected to acute psychological challenges. What’s more, they bounce back from stressful situations faster than people with low levels of vitamin C in their blood. In one study German researchers subjected 120 people to a sure-fire stress or—a public speaking task combined with math problems. Half of those studied were given 1,000 mg of vitamin C. Such signs of stress as elevated levels of the stress hormone cortisol and high blood pressure were significantly greater in those who did not get the vitamin supplement. Those who got vitamin C reported that they felt less stressed when they got the vitamin. The researchers believe that vitamin C should be considered an essential part of
stress management. Earlier studies showed that vitamin C abolished secretion of cortisol in animals that had been subjected to repeated stress. Cortisol is a hormone released by the adrenal glands in response to stress. Once it gets into the bloodstream, it is responsible for relaying the news of stress to all parts of the body and mind.

Cortisol is the hormone, for example, that triggers the fight or flight & response to stress. That allows us to spring into action when we sense danger. But like many emergency-alert systems, the stress response comes at a considerable cost. Among other effects, frequent exposure to high levels of stress hormones exhausts the body’s physical resources, impairs learning and memory, and makes people susceptible to depression. In animal studies, vitamin C fed to rats undergoing stress not only prevented the expected increase in cortisol levels, it prevented the animals from exhibiting the known signs of physical and emotional stress, including loss of body weight. Animals that did not receive vitamin C had three times the level of stress

The present RDA for vitamin C for adults is 60 – 90 milligrams—a far cry from the 1,000 mg found helpful in the stress study. But there’s a  growing belief that the RDA for vitamin C is vastly outdated. The current RDA was set decades ago and is based on the amount of the vitamin needed to ward off scurvy. Current thinking looks at vitamin C from the opposite direction: The amount needed to promote health under varying environmental conditions. That appears to be a lot greater than the amount needed to prevent deficiencies. There’s also evidence suggesting that prehistoric humans consumed large amounts of vitamin C in a tropical diet rich in fresh fruits. If so, the physiological constitution we have inherited may require far larger daily doses of vitamin C than the current RDA, perhaps as high as 1,000 mg.

Thiamin – According to the University of Maryland Medical Center, thiamine is sometimes called an anti- stress vitamin. Research has found that B1 may strengthen the immune system and improve the body’s ability to control mood and physiological impairments due to stress. Thiamine is also
used for maintaining a positive mental attitude, preventing memory loss, enhancing learning abilities, fighting stress and increasing energy. Thiamine injections can be given to patients who have a memory disorder called Wernicke’s encephalopathy.

Riboflavin – Vitamin B2 helps to calm the nervous system, regulate mood and energy, metabolizes fats/carbs.

Niacin – Anecdotally, it is claimed that niacin reduces anxiety and depression while promoting calmness and better sleep. According to Biochemical, Physiological and Molecular Aspects of Human Nutrition it is possible that niacin’s ability to increase blood flow, reduce blood pressure, eliminate excess adrenaline and regulate hormones contributes to feelings of relaxation in those who are stressed.

Pantothenic Acid – Also known as pantothenate, vitamin B 5  is sometimes referred to as the “anti-stress” vitamin because it can reverse some biological damage caused by stress. Physical, emotional, and psychological stresses trigger the adrenal glands to secrete cortisol (a long-term stress hormone) and adrenaline (a short-term stress hormone). Chronic stress drives the production of too much of any of these hormones, which causes damage in the body long after the stress signal has ended. When vitamin B 5  is present in adequate amounts, it is able to down-regulate the secretion of cortisol, and the body is able to recover. However, in a deficiency state, the adrenal glands are unable to cope. Under these circumstances, they cannot launch a healthy
response against the multiple daily stressors that affect us, and the chronic (often unavoidable) stress eventually takes a physiological toll.

Pyridoxine – The National Institute of Health found that one of the symptoms of a vitamin B6 deficiency is depression.  A study that took place and was published in “Psychotherapy and Psychosomatics”, showed that those people who were deficient in vitamin B6 manifested several symptoms of depression, including anxiety/stress. Another study published in the Canadian Journal of Psychiatry further supported the claim that a vitamin B6 deficiency can lead to mood disorders and depression.

Another important function of Vitamin B6 is to aid in the production of oxygen-carrying hemoglobin.  A deficiency has been associated with feelings of tiredness and inattentiveness, contributing to depression and sometimes anxiety.

Biotin – Stress and anxiety, when severe, can cause hair loss, premature skin aging, and weak/brittle nails. Healthy Biotin levels contribute to skin health, hair health, and strong nails. When stressed, Biotin may be at low levels, like other B vitamins. Supplementing Biotin will not reduce stress/anxiety, but it will reduce the effects of stress/anxiety – stronger nails, hair, and skin.

Folic Acid – Folate deficiency or malabsorption due to illness, taking certain medications, or other issues can increase the risk of developing major depressive disorder, as well as make it more difficult to treat. Folic acid/Folate supplementation may be beneficial for those who have major
depressive disorder that has not responded adequately to treatment with antidepressant medications.

Methylcobalamin – B12 Causes Psychiatric Symptoms: B12 deficiency can cause almost any psychiatric symptom, from anxiety, and panic to depression and hallucinations. This is because B12 deficiencies trigger symptoms in the nervous system and red blood cells. Healthy B12 levels are
foundational to managing/reducing stress/anxiety.

Vitamin E – Vitamin E is an antioxidant. Your body uses this nutrient up quickly in times of stress and anxiety. Supplementing Vitamin E helps to restore/maintain its balance, thereby reducing symptoms of stress and anxiety.


Made with KSM-66 - World's best Ashwagandha

Tranquil is an all-natural anxiety aid.  Our formula contains ingredients that research has shown to help calm and relieve stress and anxiety.

Consider taking Tranqil with Cardio Support Drops™, Strauss Heartdrops® and Kidney Support Drops™

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